Reactive species
Human;Rat;Mouse;
Antibody type
Polyclonal Antibody
Protein name
Sideroflexin-4
Immunogen
The antiserum was produced against synthesized peptide derived from human SFXN4. AA range:1-50
Specificity
Sideroflexin-4 Polyclonal Antibody detects endogenous levels of Sideroflexin-4 protein.
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000;IHC-p 1:50-300
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Other name
SFXN4; BCRM1; Sideroflexin-4; Breast cancer resistance marker 1
Background
This gene encodes a member of the sideroflexin family. The encoded protein is a transmembrane protein of the inner mitochondrial membrane, and is required for mitochondrial respiratory homeostasis and erythropoiesis. Mutations in this gene are associated with mitochondriopathy and macrocytic anemia. Alternatively spliced transcript variants have been found in this gene. [provided by RefSeq, Jan 2014],
Function
function:Potential iron transporter.,similarity:Belongs to the sideroflexin family.,