Reactive species
Human;Mouse;Rat
Applications
IHC;IF;ELISA
Antibody type
Polyclonal Antibody
Protein name
Guanylate cyclase soluble subunit beta-2
Immunogen
The antiserum was produced against synthesized peptide derived from human GCS-beta-2. AA range:53-102
Specificity
GCS-β-2 Polyclonal Antibody detects endogenous levels of GCS-β-2 protein.
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
IHC: 1/100 - 1/300. ELISA: 1/10000.. IF 1:50-200
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Other name
GUCY1B2; Guanylate cyclase soluble subunit beta-2; GCS-beta-2
Background
Nitric oxide-sensitive guanylyl cyclase is a heterodimeric enzyme consisting of an alpha and a beta subunit. The enzyme converts GTP into the second messenger cGMP and plays a major role in the cardiovascular system as a receptor for nitric oxide. Unlike other guanylyl cyclases, GUCY1B2 contains an 86-amino acid C-terminal extension with a consensus sequence for isoprenylation/carboxymethylation.
