Reactive species
Human;Rat;Mouse
Antibody type
Monoclonal antibodies
Protein name
Heat shock protein HSP 90-alpha (Heat shock 86 kDa) (HSP 86) (HSP86) (Renal carcinoma antigen NY-REN-38)
Immunogen
Synthesized peptide derived from the C-terminal region of human HSP90A. at AA range: 660-740
Specificity
The antibody detects endogenous HSP90 α protein
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
Purification process
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
Other name
Heat shock protein HSP 90-alpha (Heat shock 86 kDa;HSP 86;HSP86;Renal carcinoma antigen NY-REN-38)
Background
The protein encoded by this gene is an inducible molecular chaperone that functions as a homodimer. The encoded protein aids in the proper folding of specific target proteins by use of an ATPase activity that is modulated by co-chaperones. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012],
Function
caution:Despite classification as a pseudogene, the existence of this protein is supported by unambiguous mass spectrometry evidence.,function:Molecular chaperone.,function:Molecular chaperone. Has ATPase activity.,similarity:Belongs to the heat shock protein 90 family.,subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,subunit:Homodimer. Interacts with AHSA1, SMYD3 and TOM34. Interacts with FNIP1 and HSF1.,
