Reactive species
Human;Mouse
Antibody type
Polyclonal Antibody
Protein name
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3 mitochondrial
Immunogen
The antiserum was produced against synthesized peptide derived from human NDUFS3. AA range:117-166
Specificity
NDUFS3 Polyclonal Antibody detects endogenous levels of NDUFS3 protein.
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Other name
NDUFS3; NADH dehydrogenase [ubiquinone] iron-sulfur protein 3; mitochondrial; Complex I-30kD; CI-30kD; NADH-ubiquinone oxidoreductase 30 kDa subunit
Background
This gene encodes one of the iron-sulfur protein (IP) components of mitochondrial NADH:ubiquinone oxidoreductase (complex I). Mutations in this gene are associated with Leigh syndrome resulting from mitochondrial complex I deficiency.[provided by RefSeq, Apr 2009],
Function
catalytic activity:NADH + acceptor = NAD(+) + reduced acceptor.,catalytic activity:NADH + ubiquinone = NAD(+) + ubiquinol.,function:Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.,similarity:Belongs to the complex I 30 kDa subunit family.,subunit:Mammalian complex I is composed of 45 different subunits.,
