Reactive species
Human;Rat;Mouse;
Antibody type
Polyclonal Antibody
Protein name
Cytosolic phospholipase A2 gamma
Immunogen
The antiserum was produced against synthesized peptide derived from human PLA2G4C. AA range:301-350
Specificity
cPLA2-γ Polyclonal Antibody detects endogenous levels of cPLA2-γ protein.
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Other name
PLA2G4C; Cytosolic phospholipase A2 gamma; cPLA2-gamma; Phospholipase A2 group IVC
Background
This gene encodes a protein which is a member of the phospholipase A2 enzyme family which hydrolyzes glycerophospholipids to produce free fatty acids and lysophospholipids, both of which serve as precursors in the production of signaling molecules. The encoded protein has been shown to be a calcium-independent and membrane bound enzyme. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2009],
Function
catalytic activity:Phosphatidylcholine + H(2)O = 1-acylglycerophosphocholine + a carboxylate.,enzyme regulation:Not regulated by calcium.,function:Has a preference for arachidonic acid at the sn-2 position of phosphatidylcholine as compared with palmitic acid.,similarity:Contains 1 PLA2c domain.,tissue specificity:Highly expressed in heart and skeletal muscle.,
