Reactive species
Human;Rat;Mouse;
Antibody type
Polyclonal Antibody
Protein name
Disintegrin and metalloproteinase domain-containing protein 32
Immunogen
Synthesized peptide derived from ADAM32 . at AA range: 460-540
Specificity
ADAM32 Polyclonal Antibody detects endogenous levels of ADAM32 protein.
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Other name
ADAM32; Disintegrin and metalloproteinase domain-containing protein 32; ADAM 32
Background
ADAM metallopeptidase domain 32(ADAM32) Homo sapiens This gene encodes a member of the disintegrin family of membrane-anchored proteins that play a role in diverse biological processes such as brain development, fertilization, tumor development and inflammation. This gene is predominantly expressed in the testis. The encoded protein undergoes proteolytic processing to generate a mature polypeptide comprised of an metalloprotease, disintegrin and epidermal growth factor-like domains. This gene is located in a cluster of other disintegrin and metallopeptidase family genes on chromosome 8. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015],
Function
function:May play a role in sperm development and fertilization This is a non-catalytic metalloprotease-like protein.,similarity:Contains 1 disintegrin domain.,similarity:Contains 1 EGF-like domain.,similarity:Contains 1 peptidase M12B domain.,tissue specificity:Testis specific.,
