Reactive species
Human;Rat;Mouse;
Antibody type
Polyclonal Antibody
Protein name
DNA-directed DNA/RNA polymerase mu
Immunogen
Synthesized peptide derived from DNA Pol μ . at AA range: 210-290
Specificity
DNA Pol μ Polyclonal Antibody detects endogenous levels of DNA Pol μ protein.
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Other name
POLM; polmu; DNA-directed DNA/RNA polymerase mu; Pol Mu; Terminal transferase
Background
catalytic activity:Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).,cofactor:Magnesium.,function:Seems to act as an Ig mutase which is responsible for immunoglobulin (Ig) gene hypermutation.,similarity:Belongs to the DNA polymerase type-X family.,similarity:Contains 1 BRCT domain.,tissue specificity:Expressed in a number of tissues. Abundant in thymus.,
Function
catalytic activity:Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).,cofactor:Magnesium.,function:Seems to act as an Ig mutase which is responsible for immunoglobulin (Ig) gene hypermutation.,similarity:Belongs to the DNA polymerase type-X family.,similarity:Contains 1 BRCT domain.,tissue specificity:Expressed in a number of tissues. Abundant in thymus.,
