Reactive species
Human;Mouse;Rat
Applications
IHC;IF;ELISA
Antibody type
Polyclonal Antibody
Protein name
Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1
Immunogen
The antiserum was produced against synthesized peptide derived from human NUCKS1. AA range:28-77
Specificity
NUCKS Polyclonal Antibody detects endogenous levels of NUCKS protein.
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
IHC: 1/100 - 1/300. ELISA: 1/10000.. IF 1:50-200
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Other name
NUCKS1; NUCKS; JC7; Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1; P1
Background
This gene encodes a nuclear protein that is highly conserved in vertebrates. The conserved regions of the protein contain several consensus phosphorylation sites for casein kinase II and cyclin-dependent kinases, two putative nuclear localization signals, and a basic DNA-binding domain. It is phosphorylated in vivo by Cdk1 during mitosis of the cell cycle. [provided by RefSeq, Aug 2010],
Function
PTM:Phosphorylated by CDK1 and casein kinase. Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Translated as Arg.,
