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hnRNP LL Polyclonal Antibody

Product code: YP-Ab-01810
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Product introduction

Reactive species
Human;Mouse;Rat
Applications
WB;IHC;IF;ELISA
Antibody type
Polyclonal Antibody
Gene Name
HNRPLL
Protein name
Heterogeneous nuclear ribonucleoprotein L-like
Dalton(DA)
60kD
Immunogen
The antiserum was produced against synthesized peptide derived from human HNRPLL. AA range:241-290
Specificity
hnRNP LL Polyclonal Antibody detects endogenous levels of hnRNP LL protein.
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/20000.. IF 1:50-200
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Stockpile
-20°C/1 year
Other name
HNRPLL; SRRF; BLOCK24; Heterogeneous nuclear ribonucleoprotein L-like; hnRNPLL; Stromal RNA-regulating factor
Background
heterogeneous nuclear ribonucleoprotein L like(HNRNPLL) Homo sapiens HNRNPLL is a master regulator of activation-induced alternative splicing in T cells. In particular, it alters splicing of CD45 (PTPRC; MIM 151460), a tyrosine phosphatase essential for T-cell development and activation (Oberdoerffer et al., 2008 [PubMed 18669861]).[supplied by OMIM, Aug 2008],
Function
function:May bind RNA and play a role in mRNA processing.,similarity:Contains 3 RRM (RNA recognition motif) domains.,tissue specificity:Widely expressed. Detected in bone marrow stroma cells, skeletal muscle, heart, placenta, pancreas, kidney and lung.,

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