Reactive species
Human;Mouse
Antibody type
Polyclonal Antibody
Protein name
Eomesodermin homolog
Immunogen
The antiserum was produced against synthesized peptide derived from human EOMES. AA range:59-108
Specificity
EOMES Polyclonal Antibody detects endogenous levels of EOMES protein.
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Other name
EOMES; TBR2; Eomesodermin homolog; T-box brain protein 2; T-brain-2; TBR-2
Background
This gene belongs to the TBR1 (T-box brain protein 1) sub-family of T-box genes that share the common DNA-binding T-box domain. The encoded protein is a transcription factor which is crucial for embryonic development of mesoderm and the central nervous system in vertebrates. The protein may also be necessary for the differentiation of effector CD8+ T cells which are involved in defense against viral infections. A similar gene disrupted in mice is shown to be essential during trophoblast development and gastrulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013],
Function
similarity:Contains 1 T-box DNA-binding domain.,
