Reactive species
Human;Rat;Mouse;
Antibody type
Polyclonal Antibody
Protein name
Eosinophil cationic protein
Immunogen
The antiserum was produced against synthesized peptide derived from human ECP. AA range:102-151
Specificity
ECP Polyclonal Antibody detects endogenous levels of ECP protein.
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Other name
RNASE3; ECP; RNS3; Eosinophil cationic protein; ECP; Ribonuclease 3; RNase 3
Background
The protein encoded by this gene belongs to the pancreatic ribonuclease family, a subset of the ribonuclease A superfamily. The protein exhibits antimicrobial activity against pathogenic bacteria [provided by RefSeq, Oct 2014],
Function
disease:Induces the neurotoxic effect known as the Gordon phenomenon.,function:Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity. Possesses a wide variety of biological activities. Exhibits antibacterial activity.,similarity:Belongs to the pancreatic ribonuclease family.,subcellular location:Matrix of eosinophil's large specific granule.,