Background
This gene encodes a coiled-coil domain-containing protein that functions in mitotic spindle formation and chromosome segregation. The encoded protein plays a role in coordinating microtubule attachment by promoting recruitment of dynein proteins, and in mitotic checkpoint signaling. [provided by RefSeq, Jul 2016],
Function
mitotic sister chromatid segregation, M phase of mitotic cell cycle, establishment of mitotic spindle orientation,microtubule cytoskeleton organization, mitotic cell cycle, M phase, nuclear division, sister chromatid segregation, cell morphogenesis, cytoskeleton organization, microtubule-based process, cell cycle, chromosome segregation, mitosis,mitotic metaphase plate congression, establishment or maintenance of cell polarity, protein localization, cell cycle process, cell cycle phase, establishment of cell polarity, cellular component morphogenesis, protein localization to kinetochore, cellular protein localization, establishment of mitotic spindle localization, organelle fission, chromosome localization, chromosome organization, establishment of spindle localization, establishment of spindle orientation,establishment of chromosome localization, metaphase plate congression, organelle l
