Reactive species
Human;Rat;Mouse;
Applications
WB;IHC;IF;ELISA
Antibody type
Polyclonal Antibody
Protein name
Coiled-coil domain-containing protein 102B
Immunogen
The antiserum was produced against synthesized peptide derived from human CCDC102B. AA range:81-130
Specificity
CCDC102B Polyclonal Antibody detects endogenous levels of CCDC102B protein.
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Other name
CCDC102B; C18orf14; Coiled-coil domain-containing protein 102B
Background
CCDC102B (coiled-coil domain containing 102B), also known as AN, ACY1L or HsT1731, is a 513 amino acid protein that exists as three alternatively spliced isoforms. Widely expressed and found in multiple CNV (copy-number variant) regions, CCDC102B contains the deletion breakpoint of a maternally inherited deletion, which is 2.7 Mb in size, and maps to human chromosome 18q22.1. CCDC102B may play a role in the pathogenesis of diaphragmatic hernia, microphthalmia, colorectal carcinoma and schizophrenia. Encoding over 300 genes, chromosome 18 contains about 76 million bases. Translocation between chromosomes 18 and 14 is the most common translocation in cancers and occurs in follicular lymphomas. Niemann-Pick disease, hereditary hemorrhagic telangiectasia and erythropoietic protoporphyria are associated with chromosome 18.
