Reactive species
Human;Mouse;Rat
Antibody type
Polyclonal Antibody
Protein name
Probable D-lactate dehydrogenase, mitochondrial
Immunogen
Recombinant Protein of LDHD
Specificity
The antibody detects endogenous LDHD protein.
Constitute
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB: 1:1000-5000
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Other name
Probable D-lactate dehydrogenase, mitochondrial (DLD) (Lactate dehydrogenase D) (EC 1.1.2.4)
Background
The protein encoded by this gene belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. The similar protein in yeast has both D-lactate and D-glycerate dehydrogenase activities. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008],
Function
catalytic activity:(R)-lactate + 2 ferricytochrome c = pyruvate + 2 ferrocytochrome c.,cofactor:FAD.,similarity:Belongs to the FAD-binding oxidoreductase/transferase type 4 family.,similarity:Contains 1 FAD-binding PCMH-type domain.,subunit:Interacts with CSRP3.,tissue specificity:Expressed moderately in heart and liver and at lower levels in skeletal muscle and kidney.,