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IRF-5 Polyclonal Antibody

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IRF-5 Polyclonal Antibody

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Product code: YP-Ab-01180

Promotional price: $ 255

100UL 53UL 10UL

Product introduction

Reactive species

Human;Mouse

Applications

WB;ELISA

Antibody type

Polyclonal Antibody

Gene Name

IRF5

Protein name

Interferon regulatory factor 5 (IRF-5)

Dalton（DA）

54kD

Immunogen

Synthesized peptide derived from human protein . at AA range: 380-460

Specificity

IRF5 Polyclonal Antibody detects endogenous levels of protein.

Constitute

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source

Polyclonal, Rabbit,IgG

Dilution rate

WB 1:500-2000 ELISA 1:5000-20000

Purification process

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Stockpile

-20°C/1 year

Other name

Background

This gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Multiple transcript variants encoding different isoforms have been found for this gene, and a 30-nt indel polymorphism (SNP rs60344245) can result in loss of a 10-aa segment. [provided by RefSeq, Mar 2010],

Function

disease:Genetic variations in IRF5 are associated with susceptibility to inflammatory bowel disease type 14 (IBD14) [MIM:612245]. Inflammatory bowel disease (IBD) is a form of remitting Crohn disease (CD). CD may involve any part of the gastrointestinal tract, but most frequently the terminal ileum and colon. Bowel inflammation is transmural and discontinuous. CD is commonly classified as an autoimmune disease.,disease:Genetic variations in IRF5 are associated with susceptibility to rheumatoid arthritis (RA) [MIM:180300]. Rheumatoid arthritis is a complex, multifactorial disorder. It is one of the most common autoimmune diseases and it is characterized by inflammation of synovial tissue and joint destruction.,disease:Genetic variations in IRF5 are associated with susceptibility to systemic lupus erythematosus type 10 (SLEB10) [MIM:612251]. Systemic lupus erythematosus (SLE) is a chronic,

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IP

常规Immunoprecipitation（免疫沉淀 IP）实验操作步骤

WB

蛋白免疫印迹（WB) 实验步骤

IRF-5 Polyclonal Antibody

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IRF-5 Polyclonal Antibody

Product introduction

Product Details

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Citation

Background information

FAQ

Experimental scheme

IP

WB

Primary antibodies

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