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HMG-1 (Acetyl Lys3) rabbit pAb

Product code: YP-Ab-00907
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Product introduction

Reactive species
Human;Mouse;Rat
Applications
WB; ELISA
Antibody type
Polyclonal Antibody
Gene Name
HMGB1 HMG1
Protein name
HMG-1 (Acetyl Lys3)
Dalton(DA)
about 30kd
Immunogen
Synthesized peptide derived from human HMG-1 (Acetyl Lys3)
Specificity
This antibody detects endogenous levels of Human,Mouse,Rat HMG-1 (Acetyl Lys3)
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:1000-2000 ELISA 1:5000-20000
Purification process
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration
1 mg/ml
Stockpile
-20°C/1 year
Other name
High mobility group protein B1 (High mobility group protein 1;HMG-1)
Background
function:Binds preferentially single-stranded DNA and unwinds double stranded DNA.,similarity:Belongs to the HMGB family.,similarity:Contains 2 HMG box DNA-binding domains.,
Function
negative regulation of transcription from RNA polymerase II promoter, DNA metabolic process, DNA replication, DNA-dependent DNA replication, DNA ligation, DNA unwinding during replication, DNA repair, base-excision repair, base-excision repair, DNA ligation, DNA recombination, chromatin organization, regulation of transcription, DNA-dependent,regulation of transcription from RNA polymerase II promoter, anti-apoptosis, response to DNA damage stimulus,negative regulation of biosynthetic process, negative regulation of macromolecule biosynthetic process, negative regulation of macromolecule metabolic process, negative regulation of gene expression, regulation of cell death,negative regulation of transcription, negative regulation of transcriptional preinitiation complex assembly, negative regulation of cellular biosynthetic process, DNA geometric change, DNA duplex unwinding, cellular respo

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