Reactive species
Human;Rat;Mouse;
Applications
IHC;IF;ELISA
Antibody type
Polyclonal Antibody
Protein name
Retinol-binding protein 5
Immunogen
The antiserum was produced against synthesized peptide derived from human CRBP III. AA range:10-59
Specificity
CRBP-III Polyclonal Antibody detects endogenous levels of CRBP-III protein.
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Other name
RBP5; Retinol-binding protein 5; Cellular retinol-binding protein III; CRBP-III; HRBPiso
Background
retinol binding protein 5(RBP5) Homo sapiens The protein encoded by this gene is a cellular retinol-binding protein expressed highly in kidney and liver. Down-regulation of the encoded protein in hepatocellular carcinoma was associated with large tumor size and poor patient survival rates. [provided by RefSeq, Jul 2016],
Function
domain:Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior.,function:Intracellular transport of retinol.,similarity:Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.,tissue specificity:Higher expression in adult kidney and liver and to a lesser extent in adult and fetal spleen, adult lymph nodes and appendix, and fetal liver and kidney. Strongly decreased in hepatocellular carcinoma tissues (at protein level).,
