Home / Products / Polyclonal antibody /

RDM1 Polyclonal Antibody

Product navigation

RDM1 Polyclonal Antibody

Citation (0) Contact

Product code: YP-Ab-00519

Promotional price: $ 255

100UL 53UL 10UL

Product introduction

Reactive species

Human;Rat;Mouse;

Applications

IHC;IF;ELISA

Antibody type

Polyclonal Antibody

Gene Name

RDM1

Protein name

RAD52 motif-containing protein 1

Dalton（DA）

Immunogen

The antiserum was produced against synthesized peptide derived from human RDM1. AA range:118-167

Specificity

RDM1 Polyclonal Antibody detects endogenous levels of RDM1 protein.

Constitute

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source

Polyclonal, Rabbit,IgG

Dilution rate

IHC: 1/100 - 1/300. ELISA: 1/5000.. IF 1:50-200

Purification process

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Stockpile

-20°C/1 year

Other name

RDM1; RAD52B; RAD52 motif-containing protein 1; RAD52 homolog B

Background

This gene encodes a protein involved in the cellular response to cisplatin, a drug commonly used in chemotherapy. The protein encoded by this gene contains two motifs: a motif found in RAD52, a protein that functions in DNA double-strand breaks and homologous recombination, and an RNA recognition motif (RRM) that is not found in RAD52. The RAD52 motif region in RAD52 is important for protein function and may be involved in DNA binding or oligomerization. Alternatively spliced transcript variants encoding different isoforms have been reported. [provided by RefSeq, Jul 2008],

Function

caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,domain:C-terminal half (amino acids 134-284) contains cytoplasmic retention domains as well as determinants involved in its stress-induced nucleolar accumulation.,function:May confer resistance to the antitumor agent cisplatin. Binds to DNA and RNA.,induction:Heat-shock stress up-regulated mRNA expression of isoform 10 and isoform 11. Heat-shock stress down-regulated short N-terminal mRNA expression of isoform 2, isoform 4, isoform 6 and isoform 9.,similarity:Contains 1 RRM (RNA recognition motif) domain.,subcellular location:Isoform 1 is predominantly cytoplasmic. Isoform 3 and isoform 10 are predominantly nuclear and nucleolar. After treatment with proteasomal inhibitors and mild heat-shock stress, isoform 1, isoform 3, isoform 5, isoform 7, isoform 8 and

Open

Product Details

Customer data and reviews (0)

Fold content

Citation

Fold content

Background information

FAQ

Fold content

Experimental scheme

Fold content

IP

常规Immunoprecipitation（免疫沉淀 IP）实验操作步骤

WB

蛋白免疫印迹（WB) 实验步骤

RDM1 Polyclonal Antibody

Product navigation

RDM1 Polyclonal Antibody

Product introduction

Product Details

Customer data and reviews (0)

Citation

Background information

FAQ

Experimental scheme

IP

WB

Primary antibodies

Secondary antibodies

Elisa Kit

Biochemical kit

Recombinant protein

Antibody customization service

ELISA service

Protein service

Biochemical testing services

Literature search

Antibody application technology resources

ELISA application technology resources

Research strategies and research tools

Product literature citation

About Us

Recruit

News

Contact

Technical FAQ