Reactive species
Human;Mouse;Rat
Antibody type
Polyclonal Antibody
Protein name
Bcl-2-associated transcription factor 1
Immunogen
The antiserum was produced against synthesized peptide derived from human BCLAF1. AA range:281-330
Specificity
BTF Polyclonal Antibody detects endogenous levels of BTF protein.
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Other name
BCLAF1; BTF; KIAA0164; Bcl-2-associated transcription factor 1; Btf
Background
This gene encodes a transcriptional repressor that interacts with several members of the BCL2 family of proteins. Overexpression of this protein induces apoptosis, which can be suppressed by co-expression of BCL2 proteins. The protein localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope in cells undergoing apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
Function
function:Death-promoting transcriptional repressor.,sequence caution:Contaminating sequence. Potential poly-A sequence.,subunit:Interacts with Bcl-2 related proteins, EMD, with the adenovirus E1B 19 kDa protein and with DNA.,tissue specificity:Ubiquitous.,
