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Beclin-1 Monoclonal Antibody

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Beclin-1 Monoclonal Antibody

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Product code: YP-Ab-00086

Promotional price: $ 255

100UL 53UL 10UL

Product introduction

Reactive species

Human;Mouse;Rat;Pig;Rabbit

Applications

Antibody type

Monoclonal antibodies

Gene Name

BECN1

Protein name

Beclin-1

Dalton（DA）

52kD

Immunogen

Purified recombinant human Beclin-1 protein fragments expressed in E.coli.

Specificity

Beclin-1 Monoclonal Antibody detects endogenous levels of Beclin-1 protein.

Constitute

Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol.

Source

Monoclonal, Mouse

Dilution rate

Western Blot: 1/1000 - 1/2000. Not yet tested in other applications.

Purification process

Affinity purification

Concentration

mg/ml

Stockpile

-20°C/1 year

Other name

BECN1; GT197; Beclin-1; Coiled-coil myosin-like BCL2-interacting protein; Protein GT197

Background

beclin 1(BECN1) Homo sapiens This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015],

Function

function:Plays a central role in autophagy (By similarity). May play a role in antiviral host defense. Protects against infection by a neurovirulent strain of Sindbis virus.,similarity:Belongs to the beclin family.,subcellular location:Expressed in dendrites and cell bodies of cerebellar Purkinje cells.,subunit:Interacts with GOPC and GRID2. Interacts with AMBRA1. Probably forms a complex with AMBRA1 and PIK3C3 (By similarity). Interacts with BCL2 and BCL2L1.,tissue specificity:Ubiquitous.,

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IP

常规Immunoprecipitation（免疫沉淀 IP）实验操作步骤

WB

蛋白免疫印迹（WB) 实验步骤

Beclin-1 Monoclonal Antibody

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Beclin-1 Monoclonal Antibody

Product introduction

Product Details

Customer data and reviews (0)

Citation

Background information

FAQ

Experimental scheme

IP

WB

Primary antibodies

Secondary antibodies

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Recombinant protein

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